Prempro

Hormone Replace Therapy (HRT)
Under the guidance of the federal government, the National Heart, Lung and Blood Institute (NHLBI) launched a study to determine the long term effects of Prempro, a hormone replacement therapy drug. The study, originally planned to last eight years, was abruptly halted after five years when researchers determined the side effects were so severe they could not continue to give patients the drug.

The NHLBI study consisted of more than 16,000 women between the ages of 50 to 79. On May 31, 2002, the Data and Safety Monitoring Board made the decision to terminate the clinical trial. The board was alarmed at increases in heart problems and breast cancer among those women who were given Prempro.

According to the NHLBI, women who were given Prempro were more likely to develop serious problems compared to those in the placebo group.

• 26% increase in breast cancer
• 41% increase in strokes
• 100% increase in blood clots
• 22% increase in incidents of cardiovascular disease

Additional side effects associated with Prempro include ovarian cancer, lupus and gall bladder cancer. A study released in May 2003 by the AMA also noted increased risk of Alzheimer's disease and other forms of dementia.

Prempro Lawsuit News

April 13, 2004
Reuters reports that the benefits of hormone replacement therapy were far less than originally thought. The drugs had no role in preventing heart disease, according to the report. Reuters also noted the increased risk of stroke for those taking estrogen replacement pills.

March 2, 2004
Researchers have halted another study assessing the risks of a hormone replacement therapy drug from Wyeth. The study found that Premarin increased the risk of stroke and found that harm outweighed any potential benefits.

May 28, 2003
A study published in the AMA Journal found that Prempro doubles the risk of Alzheimer's disease and other forms of demential in women who began treatment at age 65 or older.

February 28, 2003
Wyeth announces that Prempro may be linked to memory loss.

Time Limits on Filing Suit
Every case has a statute of limitations that will apply. It varies by the type of case and the state where the case is filed. Don't wait until there is trouble or until the end of your case to get a lawyer. Your attorney would prefer to be involved every step of the way, to monitor your case, to guide you, to prevent trouble, and to assist you.

Irwin & Boesen represents persons who have been injured by dangerous drugs. Please contact us for an honest and fair evaluation of your case.